Lulexa 1% Cream

Uses of Lulexa 1% Cream

Fungal Infections

How does Lulexa 1% Cream work?

Lulexa works by killing the fungus responsible for skin infections, including athlete's foot and ringworm. It disrupts the fungal cell membrane, inhibiting ergosterol synthesis, which is vital for the membrane structure.

Side Effects of Lulexa 1% Cream

• Application Site Irritation
• Itching
• Skin Exfoliation

Quick Suggestions:

• Keep your feet clean and dry, especially between the toes where moisture can accumulate.
• Regularly wash your feet with mild soap and water.
• Cut your nails short to prevent the accumulation of fungi.
• Consider wearing open-toe shoes for daily use to promote ventilation.
• Use a separate, clean towel for your feet.
• Wear clean cotton socks and change them regularly.
• Avoid sharing socks, shoes, and towels with others to prevent the spread of infection.
• Apply an amount of Luliconazole sufficient to cover the affected area and extend 1 inch to the surrounding skin.
• Follow the prescribed dosage and frequency recommended by your doctor.
• Understand that it may take a few weeks for the infection to clear.
• Continue the full course of treatment, even if symptoms improve before completion.
• Luliconazole is a topical medication, applied externally. It is not taken orally, reducing the likelihood of systemic side effects.
• Be cautious during application to prevent contact with sensitive areas such as eyes, nose, or mouth.
• If accidental exposure occurs, rinse immediately with plenty of water.
• Inform your doctor if the infection has not cleared up after four weeks of treatment.
• Regularly follow up with your healthcare provider as recommended.

Indication:

• Luliconazole Cream, 1% is indicated for the topical treatment of interdigital tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum and Epidermophyton floccosum in patients aged 18 and older.

Pharmacology

Luliconazole, an azole-class antifungal, inhibits ergosterol synthesis by targeting lanosterol demethylase. This action leads to decreased ergosterol in fungal cell membranes, causing an accumulation of lanosterol.

Dosage & Administration:

• For topical use only; not for ophthalmic, oral, or intravaginal use.
• Interdigital Tinea Pedis: Apply a thin layer to the affected area and approximately 1 inch of the surrounding area once daily for two weeks.
• Tinea Cruris or Tinea Corporis: Apply to the affected area and surrounding area once daily for one week.

Interaction

In vitro assessment suggests luliconazole may inhibit CYP2C19 and CYP3A4, especially in moderate to severe tinea cruris. No in vivo drug interaction trials have been conducted. Luliconazole is not expected to inhibit CYPs 1A2, 2C9, and 2D6.

Contraindications

Allergy

Pregnancy & Lactation

• Pregnancy Category C. Use during pregnancy only if potential benefits justify potential risks.
• Luliconazole excretion in human milk is unknown. Caution during breastfeeding.

Precautions & Warnings

• Safety and efficacy not established in pediatric patients.
• No overall differences were observed in safety or efficacy in patients 65 and older.

Storage Conditions

Do not store above 30°C. Keep away from light and out of reach of children.